Ibuprofen Dosage Calculator

What Is Ibuprofen?

Ibuprofen (brand names: Advil, Motrin, Nurofen) is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking cyclooxygenase (COX-1 and COX-2) enzymes that produce prostaglandins — the chemical messengers responsible for pain, fever, and inflammation. Reducing prostaglandins decreases pain signal transmission, lowers body temperature set point, and reduces swelling.

Adult Dosing

For over-the-counter (OTC) use in adults and children 12 years and older:

• Pain and fever: 200–400 mg every 4–6 hours as needed
• Inflammation/arthritis: 400–800 mg every 6–8 hours (under medical supervision)
• Maximum OTC dose: 1,200 mg per day
• Maximum prescription dose: 3,200 mg per day (physician-supervised only)

Always take ibuprofen with food or milk to protect the stomach lining.

Pediatric Dosing

For children 6 months and older (not for infants under 6 months):

• Dose: 5–10 mg per kilogram body weight (mg/kg) per dose
• Maximum per dose: 400 mg
• Maximum per day: 40 mg/kg/day or 1,200 mg, whichever is less
• Dosing interval: Every 6–8 hours
• Under 6 months: Do not use ibuprofen — use only with physician approval

Liquid formulations are recommended for children. The most common concentration is 100 mg per 5 mL (equivalent to 20 mg/mL).

Important Warnings

• Kidney disease: NSAIDs reduce blood flow to the kidneys. Avoid if you have chronic kidney disease.
• Stomach: Ibuprofen irritates the stomach lining and can cause ulcers. Take with food. Avoid in active peptic ulcer disease.
• Blood thinners: Ibuprofen interacts with aspirin, warfarin, and other blood thinners — increases bleeding risk.
• Heart disease: Long-term NSAID use is associated with increased cardiovascular risk.
• Pregnancy: Avoid in the third trimester. Consult a doctor before using during any stage of pregnancy.

Ibuprofen vs Acetaminophen

Ibuprofen reduces inflammation (acetaminophen does not). Ibuprofen is harder on the stomach and kidneys. Acetaminophen is harder on the liver. For muscle aches and arthritis, ibuprofen is generally more effective.

This calculator is for educational purposes only. Always follow label directions and consult your healthcare provider.